Clinical Research Directory
Browse clinical research sites, groups, and studies.
Expanded Study of the HighLife 28mm Trans-septal Trans-catheter Mitral Valve in Patients With Moderate-severe or Severe Mitral Regurgitation and at High Surgical Risk
Sponsor: HighLife SAS
Summary
to evaluate the safety and performance of the HighLife 28mm transcatheter, trans-septal Mitral Valve in patients with moderate-severe or severe mitral regurgitation who are at high risk for surgical treatment.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
120
Start Date
2019-05-28
Completion Date
2031-12-15
Last Updated
2025-09-15
Healthy Volunteers
No
Conditions
Interventions
HighLife Transcatheter Mitral Valve Replacement
Transcatheter Mitral Valve Replacement
Locations (50)
St. Vincent's Hospital - Sydney
Darlinghurst, New South Wales, Australia
John Hunter Hospital
Newcastle, New South Wales, Australia
Macquarie University Hospital
Sydney, New South Wales, Australia
The Wesley Hospital
Auchenflower, Queensland, Australia
St. Andrew's Hospital
Adelaide, Australia
Princess Alexandra Hospital
Brisbane, Australia
Warringal Hospital
Heidelberg, Australia
The Alfred Hospital
Melbourne, Australia
John Hunter Hospital
Newcastle, Australia
Mount Hospital
Perth, Australia
North Shore Private Hospital
Sydney, Australia
ZNA Middelheim
Antwerp, Belgium
AZ Sint-Jan
Bruges, Belgium
UZ Leuven
Leuven, Belgium
Rangueil University Hospital
Toulouse, Toulouse, France
CHU Lille
Lille, France
Medipole Lyon-Villeurbanne
Lyon, France
Hopital Prive - Jacques Cartier
Massy, France
Centre Hospitalo-Universitaire de Nantes
Nantes, France
European Hospital George Pompidou
Paris, France
CHU Bordeaux
Pessac, France
CHU de Rennes
Rennes, France
Centr Cardiologiqque du Nord
Saint-Denis, France
CHRU Strasbourg
Strasbourg, France
Clinque Pasteur
Toulouse, France
Rangueil University Hospital
Toulouse, France
University Heart Center Freiburg - Bad Krozingen
Bad Krozingen, Germany
Universitaetsklinikum Bonn
Bonn, Germany
Heart Center, University Hospital Dresden
Dresden, Germany
Universitatsklink Hamburg-Eppendorf
Hamburg, Germany
Mediinisches Versorgungszentrum
Hamburg, Germany
University Hospital Heidelberg
Heidelberg, Germany
Herzentrum Leipzig
Leipzig, Germany
Deutsches Herzzentrum Munchen
Munich, Germany
University Medicine Dept of Cardiology
Rostock, Germany
University Hospital Ulm
Ulm, Germany
Medical University of Gdansk
Gdansk, Poland
Medical University of Silesia Hospital
Katowice, Poland
University Hospital of Lord's Transfiguration
Poznan, Poland
Medical University of Warsaw
Warsaw, Poland
Institute of Cardiology
Warsaw, Poland
National Heart Center Singapore
Singapore, Singapore
Royal Victoria Hospital
Belfast, United Kingdom
Brighton and Sussex University Hospital
Brighton, United Kingdom
Royal Infirmary of Edinburgh
Edinburgh, United Kingdom
Leeds Teaching Hospitals NHS Trust
Leeds, United Kingdom
University Hospitals of Leicester NHS Trust
Leicester, United Kingdom
Guy's and St. Thomas' NHS Foundation Trust - St. Thomas Hospital
London, United Kingdom
Barts Heart Center
London, United Kingdom
John Radcliffe
Oxford, United Kingdom