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QuantiFERON-CMV Test in a Prediction for Colic Cytomegalovirus Reactivation During Ulcerative Colitis
Sponsor: Centre Hospitalier Universitaire de Saint Etienne
Summary
CytoMegaloVirus (CMV) infection impairs evolution of Ulcerative Colitis (UC) leading to more severe and resistant to immunosuppressive therapies flare-up. CytoMegaloVirus (CMV) reactivation is assessed by the quantification of the CytoMegaloVirus (CMV) DeoxyriboNucleic Acid (DNA) load by real-time PCR (qPCR) in colonic biopsies; this assay is invasive and costly. The QuantiFERON-CytoMegaloVirus (QF-CMV) assay measures the immune response against CytoMegaloVirus (CMV) in a blood specimen.
Official title: Place of the QuantiFERON-CMV (QF-CMV) Test in a Prediction for Colic Cytomegalovirus Reactivation During Ulcerative Colitis (UC)
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
196
Start Date
2019-07-17
Completion Date
2026-04
Last Updated
2025-04-29
Healthy Volunteers
No
Conditions
Interventions
Biopsies
Two more biopsies in inflammatory zone will be collected.
Blood samples
Blood samples will be performed necessary at QuantiFERON-CMV (QF-CMV) test.
Locations (2)
HCL-Hôpital Lyon Sud
Lyon, France
Chu Saint-Etienne
Saint-Etienne, France