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RECRUITING
NCT04033224

Use of EBPT in Critically Ill Patients With AKI and/or Multiorgan Failure

Sponsor: Careggi Hospital

View on ClinicalTrials.gov

Summary

The use of extracorporeal blood purification therapies (EBPT) is becoming increasingly widespread worldwide in everyday clinical practice, particularly in the critical care setting. Nonetheless, most of the clinical trials aimed at exploring the effect of EBPT on patients' long-term outcomes have failed to demonstrate consistent results regarding 28 day- or hospital- mortality rates. The aim of this observational prospective registry is to evaluate if there is a cluster of critically ill patients that mostly benefits from extracorporeal blood purification therapies with different EBPTs.

Official title: Use of EBPT in Critically Ill Patients With AKI and/or Multiorgan Failure: a Multicenter Prospective Observational Registry

Key Details

Gender

All

Age Range

Any - Any

Study Type

OBSERVATIONAL

Enrollment

1000

Start Date

2019-07-16

Completion Date

2025-09-30

Last Updated

2025-02-12

Healthy Volunteers

No

Interventions

DEVICE

Commercial membrane for Extracorporeal Blood Purification Therapy (EBPT)

Every center will prescribe EBPT with commercial membranes in accordance with local practice and local levels of expertise. No variation in treatment prescription and/or treatment solutions will derive from participation in this prospective observational study. Nonetheless, every setting parameter will be recorded in the web-based registry and analyzed a-posteriori to reveal a potential correlation with the patient outcomes.

Locations (15)

Ospedale S. Giuseppe

Empoli, Firenze, Italy

Ospedale Versilia

Lido di Camaiore, Lucca, Italy

Humanitas Research Hospital

Rozzano, Milano, Italy

IRCCS Policlinico S. Donato

San Donato Milanese, Milano, Italy

Ospedale S. Gerardo

Monza, Monza-Brianza, Italy

Ospedale A. Perrino

Brindisi, Italy

Azienda Ospedaliero Universitaria Careggi

Florence, Italy

Fondazione IRCCS Policlinico San Matteo

Pavia, Italy

Ospedale S. Jacopo

Pistoia, Italy

Ospedale S. Stefano

Prato, Italy

Grande Ospedale Metropolitano "Bianchi Melacrino Morelli"

Reggio Calabria, Italy

Policlinico Universitario Fondazione Agostino Gemelli

Roma, Italy

Azienda Ospedaliero-Universitaria Sant'Andrea

Roma, Italy

Ospedale Maria Vittoria

Torino, Italy

Ospedale S. Bortolo

Vicenza, Italy