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Acute Cognitive Changes During Atrial Fibrillation Episodes (AFCOG)
Sponsor: David Brunk, PA-C, MMS
Summary
Objectives: * First, to determine if patients with a history of AF have acute measurable changes in cognitive functioning while in an episode of AF. * Second, to collect basic insight into what specific physiologic (blood pressure, pulse oximetry, heart rate, temperature) and pharmacologic (antiarrhythmic medications, rate control medications, anticoagulants, antiplatelet medications, etc.) factors minimize the neurological impact on patients while they are in AF. It is hypothesized that when using a tablet-based cognitive testing software - Cambridge Cognition (specifically to assess executive function, learning and working memory: Rapid Visual Information Processing test, Spatial Working Memory/Spatial Span Task tests, One touch Stockings of Cambridge test, Cambridge Gambling Task, Multitasking Test/Intra-Extra Dimensional Set shift tests) - a significant difference will be noted between how the patients perform while in atrial fibrillation compared to the patients' performance while in normal sinus rhythm.
Key Details
Gender
All
Age Range
35 Years - 80 Years
Study Type
OBSERVATIONAL
Enrollment
600
Start Date
2019-08-14
Completion Date
2027-01-30
Last Updated
2025-10-14
Healthy Volunteers
Not specified
Conditions
Interventions
Standard of Care Interventions to convert patient from atrial fibrillation to normal rhythm
Direct current cardioversion, PVAI-atrial fibrillation ablation, Minimally Invasive Surgical Maze procedure, Medications
Locations (1)
Penrose St. Francis
Colorado Springs, Colorado, United States