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COMPLETED
NCT04038060
NA

The PrEP (Pre-exposure Prophylaxis) SMART Study

Sponsor: University of Washington

View on ClinicalTrials.gov

Summary

The PrEP SMART study is testing a stepped model of scalable adherence support strategies in South African young women who initiate PrEP using a SMART (sequential multiple assignment randomized trial) design.

Official title: Evaluation of Stepped PrEP (Pre-exposure Prophylaxis) Adherence Support for Young South African Women Using a SMART Design

Key Details

Gender

FEMALE

Age Range

18 Years - 25 Years

Study Type

INTERVENTIONAL

Enrollment

360

Start Date

2019-05-16

Completion Date

2022-01-25

Last Updated

2026-05-04

Healthy Volunteers

Yes

Conditions

Interventions

BEHAVIORAL

WhatsApp Group

Participants will receive peer adherence support through WhatsApp groups

BEHAVIORAL

2-way SMS

Participants will receive healthcare worker adherence support through 2-way SMS

BEHAVIORAL

Drug level feedback

Participants will receive adherence counseling based on tenofovir drug levels

BEHAVIORAL

Monthly counseling sessions

Participants will receive monthly counseling on a variety of issues that may be impacting their PrEP adherence

Locations (1)

Wits Reproductive Health and HIV Institute

Johannesburg, South Africa