Clinical Research Directory
Browse clinical research sites, groups, and studies.
The PrEP (Pre-exposure Prophylaxis) SMART Study
Sponsor: University of Washington
Summary
The PrEP SMART study is testing a stepped model of scalable adherence support strategies in South African young women who initiate PrEP using a SMART (sequential multiple assignment randomized trial) design.
Official title: Evaluation of Stepped PrEP (Pre-exposure Prophylaxis) Adherence Support for Young South African Women Using a SMART Design
Key Details
Gender
FEMALE
Age Range
18 Years - 25 Years
Study Type
INTERVENTIONAL
Enrollment
360
Start Date
2019-05-16
Completion Date
2022-01-25
Last Updated
2026-05-04
Healthy Volunteers
Yes
Conditions
Interventions
WhatsApp Group
Participants will receive peer adherence support through WhatsApp groups
2-way SMS
Participants will receive healthcare worker adherence support through 2-way SMS
Drug level feedback
Participants will receive adherence counseling based on tenofovir drug levels
Monthly counseling sessions
Participants will receive monthly counseling on a variety of issues that may be impacting their PrEP adherence
Locations (1)
Wits Reproductive Health and HIV Institute
Johannesburg, South Africa