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Use of Antibiotic Irrigation to Decrease Wound Infections in Pediatric Perforated Appendicitis
Sponsor: Prisma Health-Upstate
Summary
The proposed study will investigate whether antibiotic irrigation using a gentamicin/clindamycin solution during laparoscopic appendectomy is superior in preventing postoperative wound infections and IAA in perforated appendicitis compared to suction without irrigation. This will be the first prospective study to compare these two options in pediatric PA.
Key Details
Gender
All
Age Range
0 Years - 18 Years
Study Type
INTERVENTIONAL
Enrollment
200
Start Date
2019-07-25
Completion Date
2026-12
Last Updated
2026-01-27
Healthy Volunteers
No
Conditions
Interventions
antibiotic rinse with suction
antibiotic rinse with suction
suction only
no irrigation, suction only
Locations (1)
Prisma Health - Upstate
Greenville, South Carolina, United States