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ENROLLING BY INVITATION
NCT04043442
PHASE2

rTMS Target Identification for Functional Disability in AUD+mTBI

Sponsor: VA Office of Research and Development

View on ClinicalTrials.gov

Summary

The objectives of this VA Merit application are to identify a neural target unique to Veterans with co-occurring alcohol use disorder and mild traumatic brain injury (AUD+mTBI) and to test the efficacy of this target as a stimulation site for repetitive transcranial magnetic stimulation (rTMS) treatment to maximize functional recovery. rTMS will soon be a treatment option at 30 VAs nationwide and preliminary studies show promise for AUD and mTBI treatment. A better understanding of how AUD+mTBI impacts the brain needs to occur in order to advance rTMS to optimize function. This research is aligned with the VA RR\&D's mission to generate knowledge and innovations to advance the rehabilitative health and care of Veterans, to effectively integrate clinical and applied rehabilitation research, and translate research results into practice. This research is also aligned with the goal of the Psychological Health \& Social Reintegration portfolio to develop interventions improving psychological health status of Veterans enabling them to function more fully in society.

Official title: Neural Target Identification for Functional Disability Associated With Alcohol Related Characteristics Among Veterans With Co-occurring Alcohol Use Disorder and Traumatic Brain Injury

Key Details

Gender

All

Age Range

22 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

100

Start Date

2019-01-01

Completion Date

2027-03-31

Last Updated

2026-04-08

Healthy Volunteers

No

Interventions

DEVICE

Magventure MagProX100 with MagOption stimulator and Magpro Cool Coil B65 A/P

rTMS device

Locations (1)

Edward Hines Jr. VA Hospital, Hines, IL

Hines, Illinois, United States