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Evaluation of Urinary Exosomes Presence From Clear Cell Renal Cell Carcinoma
Sponsor: Centre Hospitalier Universitaire de Saint Etienne
Summary
Clear cell renal cell carcinoma is diagnosed by imaging, sometimes associated with biopsy. This diagnosis is expensive, invasive and sometimes late. The development of a simple biological test for diagnosis is essential. Exosomes are 30 to 150 nm membrane vesicles secreted into the extracellular space by various living cells. These exosomes can be isolated from biological fluids, including urine. The recent study of urinary exosomes is a promising topic for analyzing tumor markers in urine. The investigator's goal is to develop a reliable technique for detecting tumor exosomes in urine in patients with clear cell renal cell carcinoma. The analysis of urinary exosomes could provide a new liquid biopsy tool for the early diagnosis of clear cell renal cell carcinoma.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
100
Start Date
2020-01-29
Completion Date
2026-08-01
Last Updated
2024-10-26
Healthy Volunteers
No
Conditions
Interventions
Urinary sample
Urinary sample (100 ml) will be collected in the urology department to analysis urinary exosomes.
Locations (1)
Chu Saint-Etienne
Saint-Etienne, France