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ACTIVE NOT RECRUITING
NCT04056247

Predicting Responsiveness in Oncology Patients Based on Host Response Evaluation During Anti Cancer Treatments

Sponsor: OncoHost Ltd.

View on ClinicalTrials.gov

Summary

The PROPHETIC study is a prospective, multi-center, international clinical study aimed at developing an algorithm to predict patient outcomes. The study involves analyzing the proteomic profiles of patients undergoing therapy to assess the likelihood of clinical benefit from their prescribed treatment. Blood samples are collected prior to and during the treatment period and analyzed as part of the ongoing development of thealgorithm.

Official title: PROPHETIC - Predicting Responsiveness in Oncology Patients Based on Host Response Evaluation During Anti Cancer Treatments

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

10000

Start Date

2019-10-01

Completion Date

2029-10-01

Last Updated

2025-10-15

Healthy Volunteers

No

Interventions

OTHER

Plasma sample collection

Collect at least two plasma samples

Locations (41)

Birmingham VAHCS

Birmingham, Alabama, United States

Mayo Clinic

Jacksonville, Florida, United States

University of Miami

Miami, Florida, United States

Florida Cancer Specialist and Research Institute

Orlando, Florida, United States

Protean Biodiagnosics

Orlando, Florida, United States

Northwest Community Healthcare

Rolling Meadows, Illinois, United States

Helen Nassif Community Cancer Center

Cedar Rapids, Iowa, United States

Rutgers Cancer Institute

New Brunswick, New Jersey, United States

Roswell Park

Buffalo, New York, United States

West Clinic

Germantown, Tennessee, United States

Michael E. Debakey VA Medical Center

Houston, Texas, United States

151-Christus Health St. Michael

Texarkana, Texas, United States

Asklepois

Gauting, Germany

Thoraxklinik Heidelberg gGmbH

Heidelberg, Germany

Haemek Medical Center

Afula, Israel

Barzilai Medical Center

Ashkelon, Israel

Soroka Medical Center

Beersheba, Israel

Shamir Medical Center

Be’er Ya‘aqov, Israel

Bnai Zion Medical Center

Haifa, Israel

Rambam Medical Center

Haifa, Israel

Hadassah Medcial Center

Jerusalem, Israel

Meir medical center

Kfar Saba, Israel

Rabin Medical Center

Petah Tikva, Israel

Kaplan Medical Center

Rehovot, Israel

Assuta Medical Cetner

Tel Aviv, Israel

Sheba Medical Center

Tel Aviv, Israel

Sourasky Medical Center

Tel Aviv, Israel

Sheba medical center

Tel Litwinsky, Israel

044 Hospital Universitario Virgen Macarena

Seville, Spain

Aberdeen Royal Infirmary

Aberdeen, United Kingdom

Royal Bournemouth General Hospital

Bournemouth, United Kingdom

Bradford Teaching Hospitals

Bradford, United Kingdom

Cheltenham General Hospital

Cheltenham, United Kingdom

Withybush Hospital

Haverfordwest, United Kingdom

Mount Vernon Cancer Centre

Northwood, United Kingdom

The Shrewsbury and Telford Hospital

Shrewsbury, United Kingdom

South Tyneside

South Shields, United Kingdom

Lister Hospital

Stevenage, United Kingdom

Sunderland Royal Hospital

Sunderland, United Kingdom

Swansea Bay UHB Singleton Hospital

Swansea, United Kingdom

Torbay Hospital

Torquay, United Kingdom