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ENROLLING BY INVITATION
NCT04065516
NA

ARAT for Reflux Disease After Peroral Endoscopic Myotomy in Patients With Achalasia

Sponsor: Coordinación de Investigación en Salud, Mexico

View on ClinicalTrials.gov

Summary

The peroral endoscopic myotomy for the treatment of achalasia is associated with a higher incidence of gastroesophageal reflux disease compared with Heller's myotomy. Remodeling of the esophagogastric junction with hybrid argon plasma could decrease the passage of gastric or gastroduodenal content into the esophagus.

Official title: Safety and Efficacy of Antireflux Ablation Therapy (ARAT) at Esophagogastric Junction in Patients With Reflux Disease After Peroral Endoscopic Myotomy (POEM) in Achalasia

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

44

Start Date

2019-07-03

Completion Date

2026-12-01

Last Updated

2025-04-25

Healthy Volunteers

No

Interventions

PROCEDURE

ARAT technique

After an initial endoscopic evaluation, ARAT technique will be performed with marking, submucosal elevation at esophagogastric junction and then ablation with 100-120w of 270-300 degrees at esophagogastric junction, once the application of the therapy is performed mucosal lavage and immersion technique will be made to corroborate integrity and continuity of the gastrointestinal tract and rule out immediate complications.

Locations (1)

Centro Medico Nacional Siglo XXI Hospital de Especialidades

Mexico City, Mexico City, Mexico