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RECRUITING
NCT04067505
PHASE3

Rivaroxaban for the Prevention of Deep Vein Thrombosis in Patients With Left Iliac Vein Compression - The PLICTS Study

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University

View on ClinicalTrials.gov

Summary

The purpose of this study is to evaluate the efficacy and safety of rivaroxaban for the prevention of deep vein thrombosis in patients with left iliac vein compression treated with stent implantation.

Official title: An Efficacy and Safety Study of Rivaroxaban for the Prevention of Deep Vein Thrombosis in Patients With Left Iliac Vein Compression Treated With Stent Implantation (PLICTS):A Prospective Randomized Controlled Trial

Key Details

Gender

All

Age Range

18 Years - 75 Years

Study Type

INTERVENTIONAL

Enrollment

224

Start Date

2020-05-18

Completion Date

2024-12-31

Last Updated

2024-04-18

Healthy Volunteers

No

Interventions

DRUG

Rivaroxaban

Dose: 15mg twice daily for three weeks, then 20mg once daily until six months after the operation. Application: oral

DRUG

Warfarin

Dose: 3mg for 5 days after the operation, later 0.75mg to 18mg depending on INR (2.0-3.0) until 6 months Duration: 6 months Frequency: once daily Application: oral

DRUG

Nadroparin

Dose: 1mg/kg Duration: 5 days after the operation Frequency: twice daily Application: subcutaneous

Locations (9)

Anhui Provincial Hospital

Hefei, Anhui, China

Yantai Yuhuangding Hospital

Yantai, Shangdong, China

Huadong Hospital affiliated to Fudan University

Shanghai, Shanghai Municipality, China

Shanghai 5th People's Hospital

Shanghai, Shanghai Municipality, China

Zhongshan Hospital affiliated to Fudan University

Shanghai, Shanghai Municipality, China

Sir Run Run Shaw Hospital

Hangzhou, Zhejiang, China

The second affiliated hospital of zhejiang university school of medicine

Hangzhou, Zhejiang, China

Zhejiang Provincial people's hospital

Hangzhou, Zhejiang, China

Zhejiang Xiaoshan Hospital

Hangzhou, Zhejiang, China