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ACTIVE NOT RECRUITING
NCT04070027
NA

Progressive Resistance Training Versus Total Hip Arthroplasty in Patients With Hip Osteoarthritis

Sponsor: Vejle Hospital

View on ClinicalTrials.gov

Summary

Hip osteoarthritis is associated with joint pain, physical disability, decreased muscle strength and poor health status, and the most common cause for total hip arthroplasty. No studies have investigated the effect of total hip arthroplasty compared to non-surgical treatment in patients with end-stage hip osteoarthritis. This comparison is of upmost importance as it is unknown whether non-surgical treatment may be used as an alternate to surgery. The purpose of this study is to investigate whether total hip arthroplasty followed by standard care is superior to progressive resistance training for improving hip function and pain in patients with end-stage hip osteoarthritis. The hypothesis is that patients treated with total hip arthroplasty will improve more than patients treated with progressive resistance training.

Official title: Progressive Resistance Training Versus Total Hip Arthroplasty in Patients With End-stage Hip Osteoarthritis (PROHIP): A Multicentre, Parallel-group, Randomised Controlled Superiority Trial

Key Details

Gender

All

Age Range

50 Years - Any

Study Type

INTERVENTIONAL

Enrollment

109

Start Date

2019-09-02

Completion Date

2026-06

Last Updated

2025-05-18

Healthy Volunteers

No

Interventions

PROCEDURE

Total Hip Arthroplasty

Total hip arthroplasty following standard procedures.

OTHER

Progressive Resistance Training

Progressive resistance training based on available evidence on patients with hip osteoarthritis and designed in accordance with the "American College of Sports Medicine" (ACSM) recommendations for progression models in resistance training aiming at inducing muscle hypertrophy and increasing muscle strength and power.

Locations (4)

Department of Orthopaedic Surgery, Aarhus University Hospital (AUH)

Aarhus, Denmark

Department of Orthopaedic Surgery, Naestved Hospital

Næstved, Denmark

Department of Orthopaedic Surgery and Traumatology, Odense University Hospital (OUH)

Odense, Denmark

Depatment of Orthopaedic Surgery, Vejle Hospital

Vejle, Denmark