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Progressive Resistance Training Versus Total Hip Arthroplasty in Patients With Hip Osteoarthritis
Sponsor: Vejle Hospital
Summary
Hip osteoarthritis is associated with joint pain, physical disability, decreased muscle strength and poor health status, and the most common cause for total hip arthroplasty. No studies have investigated the effect of total hip arthroplasty compared to non-surgical treatment in patients with end-stage hip osteoarthritis. This comparison is of upmost importance as it is unknown whether non-surgical treatment may be used as an alternate to surgery. The purpose of this study is to investigate whether total hip arthroplasty followed by standard care is superior to progressive resistance training for improving hip function and pain in patients with end-stage hip osteoarthritis. The hypothesis is that patients treated with total hip arthroplasty will improve more than patients treated with progressive resistance training.
Official title: Progressive Resistance Training Versus Total Hip Arthroplasty in Patients With End-stage Hip Osteoarthritis (PROHIP): A Multicentre, Parallel-group, Randomised Controlled Superiority Trial
Key Details
Gender
All
Age Range
50 Years - Any
Study Type
INTERVENTIONAL
Enrollment
109
Start Date
2019-09-02
Completion Date
2026-06
Last Updated
2025-05-18
Healthy Volunteers
No
Conditions
Interventions
Total Hip Arthroplasty
Total hip arthroplasty following standard procedures.
Progressive Resistance Training
Progressive resistance training based on available evidence on patients with hip osteoarthritis and designed in accordance with the "American College of Sports Medicine" (ACSM) recommendations for progression models in resistance training aiming at inducing muscle hypertrophy and increasing muscle strength and power.
Locations (4)
Department of Orthopaedic Surgery, Aarhus University Hospital (AUH)
Aarhus, Denmark
Department of Orthopaedic Surgery, Naestved Hospital
Næstved, Denmark
Department of Orthopaedic Surgery and Traumatology, Odense University Hospital (OUH)
Odense, Denmark
Depatment of Orthopaedic Surgery, Vejle Hospital
Vejle, Denmark