Clinical Research Directory

Inclusion Criteria: * complaint of memory loss * clinical dementia rating (CDR) scale score ≤0.5 * having normal general cognitive function screened, with MMSE ≥24 * capable of exercising safely, as determined by a healthcare provider * willingness to be randomly assigned to an intervention condition and complete the 24-week intervention and 6-month follow-up Exclusion Criteria: * having medical conditions likely to compromise survival, such as metastatic cancer, or render a participant unable to engage in physical activity, such as severe cardiac failure * participating in any type of Tai Ji Quan or daily and/or structured vigorous physical activity (i.e., brisk walking for exercise 30 minutes or longer at a time, or engaging in muscle-strengthening activities, e.g., weight lifting on 3 or more days per week 3 months prior to the study)