Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

Back to Studies
ACTIVE NOT RECRUITING
NCT04071691

PET Imaging of Giant Cell and Takayasu Arteritis

Sponsor: University of Cambridge

View on ClinicalTrials.gov

Summary

While 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) imaging is often included in the diagnostic work-up of patients with large-vessel vasculitis (LVV), 18F-FDG lacks specificity for inflammatory cells and has limited ability to track therapy response. Moreover, high background 18F-FDG uptake in the brain and myocardium largely precludes imaging temporal arteritis in giant-cell arteritis (GCA) and coronary artery involvement in Takayasu arteritis respectively. These limitations of 18F-FDG for imaging LVV highlight important unmet clinical needs, which might be overcome by using a somatostatin receptor subtype-2 (SST2) PET tracer.

Official title: The PET Imaging of Giant Cell and Takayasu Arteritis Study

Key Details

Gender

All

Age Range

18 Years - 99 Years

Study Type

OBSERVATIONAL

Enrollment

27

Start Date

2019-06-25

Completion Date

2025-04

Last Updated

2024-07-22

Healthy Volunteers

No

Interventions

DIAGNOSTIC_TEST

PET-MRI

SST2 PET-MRI scan

Locations (2)

University of Cambridge

Cambridge, Cambridgeshire, United Kingdom

Imperial College Healthcare NHS Trust

London, United Kingdom