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Non-invasive Markers of Esophageal Function in Adults
Sponsor: Vanderbilt University Medical Center
Summary
The investigator proposes to study electrical activity reflective of esophageal motility in adults noninvasively by the use of multichannel electroesophagogram (EESG) and magnetoesophagogram (MESG) recordings.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
90
Start Date
2019-09-04
Completion Date
2026-09
Last Updated
2025-09-05
Healthy Volunteers
Yes
Conditions
Interventions
Clinical measure questionnaires
Collection of patient reported symptoms and perception of health
EESG
Use of silver-silver chloride cutaneous electrogastrogram (EGG) electrodes to get myoelectrical readings
MESG
MESG measures spatiotemporal properties of magnetic fields from the esophageal slow wave and allows characterization of the propagation of the slow wave in addition to evaluation of its frequency and power distribution
High resolution manometry (HRM)
Dysphagia subjects will have undergone standard of care HRM to determine placement in the achalasia or hypercontractile/spastic disorder arms
Locations (1)
Vanderbilt University Medical Center
Nashville, Tennessee, United States