Clinical Research Directory

Inclusion Criteria: * Patients scheduled to undergo primary total knee replacement: * with painful and disabled knee joint resulting from any of the following diagnoses: * Osteoarthritis, * Traumatic arthritis, * Rheumatoid arthritis with one or more compartments involved. * Correction of varus, valgus, or posttraumatic deformity. * Correction or revision of unsuccessful osteotomy or arthrodesis. * Need to obtain pain relief and improve function. * Ability and willingness to follow instructions, including control of weight and activity level, and to return for follow-up evaluations. * A good nutritional state of the patient. * Full skeletal maturity of the patient, patients who are at least 18 years of age. * Patients of either sex. * Consent form read, understood, and signed by patient. Exclusion Criteria: * Absolute contraindications include the following diagnoses: * Infection * Osteomyelitis * Previous partial or total prosthetic knee replacement on the operative side * Skeletal immaturity of the patient * Sepsis * Patients who are less than 18 years of age * Relative contraindications include: * uncooperative patient or patient with neurologic disorders who are incapable of following directions, * osteoporosis, * metabolic disorders which may impair bone formation, * osteomalacia, * distant foci of infections which may spread to the implant site, * rapid joint destruction, marked bone loss or bone resorption apparent on roentgenogram, * vascular insufficiency, muscular atrophy, neuromuscular disease, * incomplete or deficient soft tissue surrounding the knee