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PLATO - Medication Adherence in Transplant Recipients
Sponsor: University of British Columbia
Summary
Non-adherence with immunosuppressant drugs is a major reason for premature kidney transplant failure. Currently, patient education and compliance aids (e.g bubble packing) are commonly used to assist patients. This is a study involving patients expected to undergo a kidney transplant within 6 months. One group will undergo a one-month formal assessment of adherence before transplantation using mock immunosuppressant medication. Standardized surveys will also be administered to assess risk factors for non-adherence. A plan will be developed for use after the transplant. The other group will undergo usual care. Kidney function and rejection rates will be compared between two groups.
Official title: Pre-Transplant Multidisciplinary Assessment on Medication Adherence and Transplant Outcomes
Key Details
Gender
All
Age Range
19 Years - Any
Study Type
INTERVENTIONAL
Enrollment
99
Start Date
2019-09-10
Completion Date
2024-12-31
Last Updated
2024-05-13
Healthy Volunteers
No
Interventions
Tailored medication adherence plan
Comparison of mean daily medication adherence between intervention and control groups over 3 months, as measured by MEMS caps.
Locations (2)
Vancouver General Hospital
Vancouver, British Columbia, Canada
St. Paul's Hospital
Vancouver, British Columbia, Canada