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LASER and Radiofrequency for Treatment of Vaginal Vulvar Atrophy (VVA) in Women Treated for Breast Cancer (EPMLARF-arm2)
Sponsor: Federal University of São Paulo
Summary
This is a randomized controlled trial to evaluate the use of LASER, Micro Ablative radiofrequency and topic promestriene to treat symptoms of vulvovaginal atrophy of women treated for breast cancer.
Official title: LASER and Radiofrequency as Alternative Treatment of Vaginal Vulvar Atrophy in Women Treated for Breast Cancer
Key Details
Gender
FEMALE
Age Range
30 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
195
Start Date
2019-09-30
Completion Date
2025-09
Last Updated
2025-04-24
Healthy Volunteers
No
Interventions
LASER
The patient will use intravaginal estriol, daily for 2 weeks and them twice a week for 3 months . Each 30 days, the patients will have an appointment when will be checked the weight of the estriol tube to verify the correct use.vulvar application of LASER, to postmenopausal genitourinary syndrome. The patient will be in gynecological position, after remove of vaginal secretion, with gauze and under topic anesthesia, the LASER will be applied, according to the protocol of the manufactured.
Micro Ablative Radiofrequency
Use of Linly™ equipment to perform ambulatory intravaginal and vulvar application of fractionated microablative radiofrequency, to postmenopausal genitourinary syndrome. The patient will be in gynecological position, after remove of vaginal secretion, with gauze and under topic anesthesia, the radiofrequency will be applied, according to the protocol of the manufactured
Promestriene
The patient will perform self application of this vaginal promestriene daily for 2 weeks and after that the applications will occur twice a week.
Locations (1)
Federal University of Sao Paulo - Unifesp
São Paulo, São Paulo, Brazil