Clinical Research Directory

Participants with CKD Inclusion Criteria: 1. Age Over 18 years of age 2. Estimated GFR 59-15ml/min/1.73m² or eGFR \>60ml/min/1.73m² and urine albumin to creatinine ratio \>30mg/mmol 3. Seen at least once in a Nephrology Clinic 4. Willing to participate in two study visits 5. Able to give informed consent and participate in study procedures Exclusion Criteria: 1. Recipient of a solid organ transplant 2. Expected survival less than 1 year (in the opinion of local investigators) 3. Acute kidney injury within 3 months of recruitment 4. Major Acute Cardiovascular Event (MACE) within 3 months of recruitment Participants without CKD - controls Inclusion criteria 1. Age over 18 years of age 2. Willing to participate in one study visit 3. Able to give informed consent and participate in study procedures 4. No evidence of CKD 5. No other major illnesses except for hypertension and type 2 diabetes mellitus (50 participants will have diabetes but no CKD) Exclusion criteria 1. Estimated GFR\<60ml/min/1.73m2 in previous 12 months or last available result 2. Urine albumin to creatinine ratio \>3mg/mmol in previous 12 months or last available result 3. Previous unilateral nephrectomy or partial nephrectomy 4. Recipient of a solid organ transplant 5. Expected survival less than 1 year (in the opinion of local investigators)