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Breast Screening - Risk Adaptive Imaging for Density
Sponsor: University of Cambridge
Summary
BRAID is a randomised, multi-centre study assessing the impact of supplementary imaging in the detection of breast cancer in women participating in the UK national breast screening programme who have dense breast tissue.
Key Details
Gender
FEMALE
Age Range
50 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
9000
Start Date
2019-05-28
Completion Date
2025-10-31
Last Updated
2025-03-30
Healthy Volunteers
No
Conditions
Interventions
ABUS
Automated whole breast ultrasound (ABUS) is undertaken with a large transducer panel placed on the breast in three positions. Resultant images are combined to make a 3D image of the breast.
CEM
A high kV and a low kV image is taken in two standard views of each breast following the intravenous injection of an iodinated contrast agent.
ABB-MRI
ABB-MRI is a shorter version of breast MRI. Standard T1W pre and post contrast images are acquired. A MIP and post-contrast T1 weighted image are read.
Locations (10)
Tayside Health Board, Ninewells Hospital
Dundee, Dundee, United Kingdom
Greater Glasgow Health Board, Gartnavel Royal Hospital
Glasgow, Glasgow, United Kingdom
University Hospitals of Leicester, Leicester Royal Infirmary
Leicester, Leicestershire, United Kingdom
Barts Health NHS Trust, Royal London Hospital
London, London, United Kingdom
Royal Free London NHS Foundation Trust
London, London, United Kingdom
Nottingham University Hospitals NHS Trust, City Hospital
Nottingham, Nottinghamshire, United Kingdom
Cambridge University Hospitals NHS Foundation Trust
Cambridge, United Kingdom
Gloucestershire Hospitals NHS Foundation Trust
Cheltenham, United Kingdom
The Leeds Teaching Hospitals NHS Trust
Leeds, United Kingdom
Manchester University NHS Foundation Trust
Manchester, United Kingdom