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Epidemiology of Carbapenemase-producing Bacteria in a Swiss Tertiary Care Hospital
Sponsor: University Hospital, Basel, Switzerland
Summary
This retrospective and prospective study is to investigate the incidence of Carbapenemase-producing bacteria (CPB) at the University Hospital Basel, the time to detection of CPB and to initiation of infection control measures, the risk factors associated with carriage of CPB, type and duration of previously administrated antibiotic medication, antibiotic treatment, as well as to assess the outcomes of the affected patients.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
100
Start Date
2019-08-22
Completion Date
2029-06-30
Last Updated
2024-12-13
Healthy Volunteers
No
Conditions
Interventions
data collection for demographic data
data collection for demographic data (age, gender, hospital admission and discharge date, length of stay, hospitalization prior to current hospital stay (acute care facilities, long-term healthcare centres, nursing homes), discharge destination, outcome, cause of death, travel history, previous exposure to antibiotics and proton pump Inhibitors)
data collection for clinical data
data collection for clinical data (comorbidities, Charlson Comorbidity Index, immunosuppressive treatment, date of diagnosis of CPB, days between hospital admission and diagnosis of CPB, type of consecutive infection, indwelling vascular hardware, urinary catheterization, surgical therapies)
data collection for treatment data
data collection for treatment data (antibiotic therapy, immunosuppressive therapy, concomitant medication)
data collection for microbiological data
data collection for microbiological data (species of CPB, type of sample, date of sample, history of colonization or infection with any antibiotic resistant pathogen)
Locations (1)
Division of Infectious Diseases and Hospital Epidemiology
Basel, Switzerland