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ENROLLING BY INVITATION
NCT04098640
NA

Molecular Profiling in Young (<50 Years of Age) Patients With Metastatic Breast Cancer

Sponsor: Seoul National University Hospital

View on ClinicalTrials.gov

Summary

Breast cancer is the most common cancer in women worldwide, especially in developed countries. In developing countries, including South Korea, the incidence and mortality rate of breast cancer is rapidly increasing. One of the most important characteristics of breast cancer in South Korea, as well as in other Asian countries, is the younger onset of disease compared to Western. Medical treatment of breast cancer is evolving rapidly, incorporating immune checkpoint blockades and molecularly targeted agents. However, data and knowledge are still limited in terms of molecular characteristics of Asian breast cancer, compared to that of Western countries, and this remains a major hurdle for drug development in Asian breast cancer patients. The primary objective of this study is to elucidate the genetic characteristic of young (\<50 years of age) Korean patients with metastatic breast cancer using FoundationOne CDx.

Official title: Molecular Profiling Using FoundationOne CDx in Young (<50 Years of Age) Patients With Metastatic Breast Cancer (ML41263)

Key Details

Gender

FEMALE

Age Range

19 Years - 50 Years

Study Type

INTERVENTIONAL

Enrollment

200

Start Date

2019-09-23

Completion Date

2025-12-31

Last Updated

2025-04-17

Healthy Volunteers

No

Conditions

Interventions

GENETIC

FoundationOne CDx

FoundationOne CDx will be performed using archival tumor tissue

Locations (1)

Seoul National University Hospital

Seoul, Seoul, South Korea