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Molecular Profiling in Young (<50 Years of Age) Patients With Metastatic Breast Cancer
Sponsor: Seoul National University Hospital
Summary
Breast cancer is the most common cancer in women worldwide, especially in developed countries. In developing countries, including South Korea, the incidence and mortality rate of breast cancer is rapidly increasing. One of the most important characteristics of breast cancer in South Korea, as well as in other Asian countries, is the younger onset of disease compared to Western. Medical treatment of breast cancer is evolving rapidly, incorporating immune checkpoint blockades and molecularly targeted agents. However, data and knowledge are still limited in terms of molecular characteristics of Asian breast cancer, compared to that of Western countries, and this remains a major hurdle for drug development in Asian breast cancer patients. The primary objective of this study is to elucidate the genetic characteristic of young (\<50 years of age) Korean patients with metastatic breast cancer using FoundationOne CDx.
Official title: Molecular Profiling Using FoundationOne CDx in Young (<50 Years of Age) Patients With Metastatic Breast Cancer (ML41263)
Key Details
Gender
FEMALE
Age Range
19 Years - 50 Years
Study Type
INTERVENTIONAL
Enrollment
200
Start Date
2019-09-23
Completion Date
2025-12-31
Last Updated
2025-04-17
Healthy Volunteers
No
Conditions
Interventions
FoundationOne CDx
FoundationOne CDx will be performed using archival tumor tissue
Locations (1)
Seoul National University Hospital
Seoul, Seoul, South Korea