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Advancing Postmenopausal Preventive Therapy
Sponsor: University of Southern California
Summary
Advancing Postmenopausal Preventive Therapy (APPT) is a randomized, double-blinded, placebo-controlled trial designed to determine the effects of tissue selective estrogen complex (TSEC) therapy on the progression of subclinical atherosclerosis and cognitive decline in 360 healthy postmenopausal women.
Official title: Atherosclerosis Intervention With Novel Tissue Selective Estrogen Complex Therapy
Key Details
Gender
FEMALE
Age Range
45 Years - 59 Years
Study Type
INTERVENTIONAL
Enrollment
385
Start Date
2021-04-13
Completion Date
2026-12-31
Last Updated
2024-12-05
Healthy Volunteers
Yes
Conditions
Interventions
Oral bazedoxifene 20 mg / conjugated estrogens 0.45 mg
Oral bazedoxifene 20 mg / conjugated estrogens 0.45 mg
Placebo
Placebo
Locations (1)
University of Southern California Atherosclerosis Research Unit
Los Angeles, California, United States