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COMPLETED
NCT04109820
NA

Effect of MitoQ on Platelet Function and Reactive Oxygen Species Generation in Patients With Sickle Cell Anemia

Sponsor: University of Pittsburgh

View on ClinicalTrials.gov

Summary

MitoQ is commercially available as a dietary supplement and it has been tested as a potential drug in other diseases, but it has never been tested in patients with sickle cell disease. The goal of this research is to study if MitoQ, a molecule that works as an antioxidant by removing potentially damaging agents in a living organism, improves platelet function in patients with sickle cell disease (SCD).

Official title: Effect of MitoQ on Platelet Function and Reactive Oxygen Species (ROS) Generation in Patients With Sickle Cell Anemia

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

18

Start Date

2020-03-10

Completion Date

2025-06-30

Last Updated

2026-09-02

Healthy Volunteers

Yes

Interventions

DIETARY_SUPPLEMENT

MitoQ

Oral; 20mg once a day for 14 days

Locations (5)

Magee Women's Hospital

Pittsburgh, Pennsylvania, United States

UPMC Montefiore

Pittsburgh, Pennsylvania, United States

UPMC Presbyterian

Pittsburgh, Pennsylvania, United States

Children's Hospital of Pittsburgh

Pittsburgh, Pennsylvania, United States

Hillman Cancer Center

Pittsburgh, Pennsylvania, United States