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An International, Multicenter, Prospective Registry on Post-traumatic Long Bones Defects
Sponsor: AO Innovation Translation Center
Summary
Long bone defect (LBD) is defined as a focalized loss of bone tissue in any long bone of the upper or lower extremity. Long bone defects are a complex problem, that may arise as a complication of many different pathologies, such as trauma, tumors or infection. Whereas post-traumatic defects are the largest group. Reports estimate that there are almost 4 million bone grafting procedures worldwide per year. However, limb reconstruction in the context of a bony defect is challenging and up to date there is little evidence and treatment recommendations. In a multi-national approach, the aim of this project is to set up an international, multicenter registry to gather information and details on prevalence or incidence, current treatments, complications and outcome.
Official title: An International, Multicenter, Prospective Registry to Investigate Treatment Options and Their Outcomes on Post-traumatic Long Bones Defects
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
600
Start Date
2024-07-03
Completion Date
2029-03-30
Last Updated
2025-08-29
Healthy Volunteers
No
Conditions
Interventions
Any treatment that is used for a defect of any long bone
Any treatment that is used for a defect of any long bone. All treatments are based on individual clinician's judgement and the patient characteristics. The registry does not dictate any specific treatment.
Locations (21)
Cedar Sinai
Los Angeles, California, United States
Sinai Hospital of Baltimore
Baltimore, Maryland, United States
John Hunter Hospital
Newcastle, Australia
Hospital Municipal Miguel Couto Serviço de Ortopedia e Traumatologia
Rio de Janeiro, Brazil
Hospital Base Valdivia
Valdivia, Chile
Hospital Universitario de la Samaritana
Bogotá, Colombia
Hospital Pablo Tobon Uribe
Medellín, Colombia
University Hospital Frankfurt
Frankfurt, Germany
Universitätsspital Gießen
Giessen, Germany
Universitätsklinikum Heidelberg (Unfallchirurgie)
Heidelberg, Germany
Universitätsklinikum Münster (Klinik und Poliklinik für Unfall-, Hand- und Wiederherstellungschirurgie)
Münster, Germany
Krankenhaus Johanneum
Wildeshausen, Germany
Paras HMRI Hospital Patna
Patna, India
Academisch Ziekenhuis Maastricht (Dept. of Surgery)
Maastricht, Netherlands
Radboud University Medical Center
Nijmegen, Netherlands
Tygerberg Hospital
Cape Town, South Africa
Kyungpook National University Hospital (Orthopaedics)
Daegu, South Korea
Universitätsspital Zürich (Klinik für Traumatologie)
Zurich, Switzerland
Central Hospital of Border Guard Service of Ukraine
Kyiv, Ukraine
Leeds General Infirmary University Hospital (Trauma & Orthopaedic Surgery)
Leeds, United Kingdom
Hospital Universitario de Caracas
Caracas, Venezuela