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Stereotactic Magnetic Resonance Guided Radiation Therapy
Sponsor: Dana-Farber Cancer Institute
Summary
This is a master prospective Phase I-II trial evaluating feasibility and efficacy of stereotactic magnetic resonance (MR) guided adaptive radiation therapy (SMART) in patients with cancer. * The phase 1 study will evaluate the feasibility and safety of delivering SMART in patients with cancer. * Phase 2 will evaluate efficacy of SMART with specific reference to tumor control and improvement in patient reported outcome measures
Official title: A Master Protocol of Stereotactic Magnetic Resonance Guided Adaptive Radiation Therapy (SMART)
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
397
Start Date
2019-10-22
Completion Date
2028-06
Last Updated
2025-11-13
Healthy Volunteers
No
Conditions
Interventions
MR-guided Linac
Radiation will be delivered on an MR-guided Linear Accelerator
Locations (2)
Brigham & Women's Hospital
Boston, Massachusetts, United States
Dana Farber Cancer Institute
Boston, Massachusetts, United States