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DNA Repair Activity in the Skin of Day and Night Shift Workers
Sponsor: Wright State University
Summary
The purpose of this study is to test how the skin of night shift workers responds to artificial sunlight (ultraviolet B radiation; UVB) at two different times of the day in comparison to normal day shift workers. After the skin biopsies are obtained, they will be brought to the laboratory to be exposed to UVB radiation and to measure UVB responses.
Official title: Pilot Study on DNA Repair Activity in the Skin of Day and Night Shift Workers
Key Details
Gender
All
Age Range
18 Years - 40 Years
Study Type
INTERVENTIONAL
Enrollment
48
Start Date
2022-12-07
Completion Date
2025-12
Last Updated
2025-02-06
Healthy Volunteers
Yes
Conditions
Interventions
Ultraviolet B Radiation
One skin punch biopsy will be taken to the laboratory for exposure to ultraviolet B radiation. After 1-hour incubation, the biopsies will be bisected in half.
No Ultraviolet B Radiation
One skin punch biopsy will be taken to the laboratory and will be kept as a non-irradiated control.
Locations (1)
Wright State Physicians
Fairborn, Ohio, United States