Clinical Research Directory

INCLUSION CRITERIA: Inclusion Criteria for All Participants: * Normal or corrected to normal vision and hearing * Verbal and written fluency in English * Right-handed * Body mass index of 20-35 kg/m\^2 Additional Inclusion Criteria for Participants with Binge-Eating Disorder: • DSM-5 binge-eating disorder EXCLUSION CRITERIA: Exclusion Criteria for All Participants: * Impaired cognition or other neurological/cognitive problems * Contraindications to MRI (e.g., certain metal implants, claustrophobia) * Currently/recently/potentially pregnant, seeking to become pregnant in the near future, or breastfeeding * Serious and/or unstable medical diseases and conditions, and certain other medical diseases and conditions * Recent low weight * Certain medications (e.g., insulin) * Current/recent frequent recreational drug use, or history of frequent recreational drug use in early adolescence * Extreme dietary limitations (e.g., veganism), pervasive food allergies, or limited exposure to popular snack foods * Current/recent suicidality * Current/recent changes in treatment for mental illness * Study-relevant research experience Additional Exclusion Criteria for Comparison Participants: * Personal history of eating disorders or recurrent binge eating * Personal history of any other mental illness, including serious substance use problems * First-degree relative with current or past eating or psychotic disorder * Significant recent change in weight Additional Exclusion Criteria for Participants with Binge-Eating Disorder: * Severe mental illness (e.g., psychotic disorder, severe agoraphobia) * Certain other current/recent mental illness, including severe substance use problems, that would limit study participation or safety * Recent anorexia nervosa spectrum disorder, avoidant-restrictive food intake disorder, or bulimia nervosa spectrum disorder