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adaptatiVe Endovascular Strategy to the CloT MRI in Large Intracranial Vessel Occlusion
Sponsor: Nantes University Hospital
Summary
In the VECTOR trial, the aim is to analyze, in case of SVS+ occlusions, a first line Embotrap II added to CA combined strategy compare to CA alone strategy. Many practitioners are convinced that a first line strategy with CA alone is easy, safe, rapid and efficient. Maybe, after two, three, four ... passes and with the secondary help of a combined strategy, a high rate of eTICI 2b/3 could be reached with a CA first line strategy. But this could go with a higher number of passes, a waste of time and a suboptimal angiographic results (eTICI 2b) due to distal emboli, especially in case of friable, non-well organized, red blood cell rich (RBC) i.e. SVS + thrombi (25-28). This could, be related to worst clinical outcome at 3 months. VECTOR asks a relevant question: Do the invetigators have to add the use of an Embotrap II or III to the CA, from the first passes, in case of SVS+ clots?
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
526
Start Date
2019-11-26
Completion Date
2022-10-03
Last Updated
2026-09-14
Healthy Volunteers
No
Conditions
Interventions
combined EMBOTRAP II or III and Contact Aspiration
refer to title
Contact Aspiration alone
refer to title
Locations (23)
CHU Amiens-Picardie
Amiens, France
CH Angers
Angers, France
CH Côte Basque
Bayonne, France
Hôpital Pellegrin - CHU Bordeaux
Bordeaux, France
CHRU Brest
Brest, France
Hôpital Bicêtre
Le Kremlin-Bicêtre, France
Hôpital Roger Salengro - CHR Lille
Lille, France
CHU Limoges
Limoges, France
Hospices Civils Lyon
Lyon, France
CHU Marseille - Hôpital la Timone
Marseille, France
CHU Gui de Chauliac
Montpellier, France
CHU Nancy
Nancy, France
CHU de Nantes
Nantes, France
Fondation Ophtalmologique Adolphe de Rothschild
Paris, France
Hôpital Ste Anne
Paris, France
La Pitié Salpétrière
Paris, France
CH PAU
Pau, France
Hôpital Maison Blanche - CHU Reims
Reims, France
Hôpital Pontchaillou - CHU Rennes
Rennes, France
CHU Strasbourg
Strasbourg, France
Hôpital FOCH
Suresnes, France
Hôpital Bretonneau - CHU Tours
Tours, France
CH Bretagne Atlantique
Vannes, France