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COMPLETED
NCT04139486
NA

adaptatiVe Endovascular Strategy to the CloT MRI in Large Intracranial Vessel Occlusion

Sponsor: Nantes University Hospital

View on ClinicalTrials.gov

Summary

In the VECTOR trial, the aim is to analyze, in case of SVS+ occlusions, a first line Embotrap II added to CA combined strategy compare to CA alone strategy. Many practitioners are convinced that a first line strategy with CA alone is easy, safe, rapid and efficient. Maybe, after two, three, four ... passes and with the secondary help of a combined strategy, a high rate of eTICI 2b/3 could be reached with a CA first line strategy. But this could go with a higher number of passes, a waste of time and a suboptimal angiographic results (eTICI 2b) due to distal emboli, especially in case of friable, non-well organized, red blood cell rich (RBC) i.e. SVS + thrombi (25-28). This could, be related to worst clinical outcome at 3 months. VECTOR asks a relevant question: Do the invetigators have to add the use of an Embotrap II or III to the CA, from the first passes, in case of SVS+ clots?

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

526

Start Date

2019-11-26

Completion Date

2022-10-03

Last Updated

2026-09-14

Healthy Volunteers

No

Interventions

PROCEDURE

combined EMBOTRAP II or III and Contact Aspiration

refer to title

PROCEDURE

Contact Aspiration alone

refer to title

Locations (23)

CHU Amiens-Picardie

Amiens, France

CH Angers

Angers, France

CH Côte Basque

Bayonne, France

Hôpital Pellegrin - CHU Bordeaux

Bordeaux, France

CHRU Brest

Brest, France

Hôpital Bicêtre

Le Kremlin-Bicêtre, France

Hôpital Roger Salengro - CHR Lille

Lille, France

CHU Limoges

Limoges, France

Hospices Civils Lyon

Lyon, France

CHU Marseille - Hôpital la Timone

Marseille, France

CHU Gui de Chauliac

Montpellier, France

CHU Nancy

Nancy, France

CHU de Nantes

Nantes, France

Fondation Ophtalmologique Adolphe de Rothschild

Paris, France

Hôpital Ste Anne

Paris, France

La Pitié Salpétrière

Paris, France

CH PAU

Pau, France

Hôpital Maison Blanche - CHU Reims

Reims, France

Hôpital Pontchaillou - CHU Rennes

Rennes, France

CHU Strasbourg

Strasbourg, France

Hôpital FOCH

Suresnes, France

Hôpital Bretonneau - CHU Tours

Tours, France

CH Bretagne Atlantique

Vannes, France