Clinical Research Directory
Browse clinical research sites, groups, and studies.
Summary
Severe muscle loss in patients with cancer has been associated with increased physical disability, extended hospitalization, infectious and noninfectious complications, increased risk of severe toxicity during cancer treatment, poor quality of life and shortened survival. Adequate protein is key to sustain muscle mass and overall health. However, current nutritional recommendations are not specific or evidence-based. The aim of this project is to determine the protein needs of patients with colorectal or breast cancer. Protein needs will be determined using a novel, non-invasive approach. Our results will inform nutritional recommendations and guidelines with the ultimate goal of improving outcomes for people with cancer.
Official title: Innovative Approaches to the Lack of Evidence-based Dietary Protein Requirements for Patients With Cancer
Key Details
Gender
All
Age Range
45 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
40
Start Date
2021-04-26
Completion Date
2025-12-31
Last Updated
2024-12-16
Healthy Volunteers
No
Conditions
Interventions
Phenylalanine intake
Oral consumption of eight hourly experimental meals- Includes 4 tracer-free experimental meals containing a mixture of free amino acids, calories from a flavored liquid and protein-free cookies and 4 labeled amino acid experimental meals.
Locations (1)
University of Alberta
Edmonton, Alberta, Canada