Clinical Research Directory

Inclusion Criteria: * Provide signed and dated informed consent form * Male or female, ages 8-22 * Current diagnosis of Eosinophilic Esophagitis (≥ 15 eos/HPF) within the last 6 months * Able to swallow pills or open capsule to take medication with apple sauce * Weight \>20kg * Willing to undergo unsedated transnasal endoscopy (TNE) Exclusion Criteria: * Inability or unwillingness of participant to give written informed consent or comply with study protocol. * Have a known bleeding disorder * Current topical esophageal corticosteroid or systemic steroid treatment within past 8 weeks * No therapy with H2 therapy within the past 16 weeks * Planned or anticipated change in the diet during the study duration. * Planned or anticipated change in other corticosteroid medications * Uncontrolled cough, rhinorrhea, rhinitis obstructing nasal passages, GI illness or determination of significant illness at screening * Pregnancy, breast feeding or plans to become pregnant * Use of investigational drug within last 16 weeks * Allergy to any medications used for procedures * Allergy to PPI * Past or current medical problems or findings from physical exam or laboratory testing that are not listed above, which, in the opinion of the investigator, may pose additional risks from participation in the study, may interfere with participant's ability to comply with study requirements, or that may impact the quality or interpretation of the data obtained from the study