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ACT NOW Longitudinal Study: Outcomes of Babies With Opioid Exposure Study
Sponsor: Advancing Clinical Trials in Neonatal Opioid Withdrawal (ACT NOW) Program
Summary
The objective of this longitudinal cohort study is to quantify the effects of antenatal opioid exposure on the trajectory of brain development over the first 2 years of life, examine associations with developmental and neurobehavioral outcomes, and explore how specific factors (differing antenatal and postnatal exposures, severity of neonatal opioid withdrawal, maternal stress/depression/parenting) modify these effects
Key Details
Gender
All
Age Range
Any - 1 Month
Study Type
OBSERVATIONAL
Enrollment
300
Start Date
2020-08-19
Completion Date
2026-12
Last Updated
2025-01-29
Healthy Volunteers
Yes
Conditions
Locations (6)
University of Alabama at Birmingham
Birmingham, Alabama, United States
Children's National Medical Center
Washington D.C., District of Columbia, United States
RTI International
Durham, North Carolina, United States
Cincinnati Children's Medical Center
Cincinnati, Ohio, United States
Case Western Reserve University, Rainbow Babies and Children's Hospital
Cleveland, Ohio, United States
Univeristy of Pennsylvania
Philadelphia, Pennsylvania, United States