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Idebenone for the Preventive Treatment of Migraine
Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University
Summary
Idebenone improves energy metabolism similarly to Coenzyme Q10, which is effective in migraine prophylaxis. The investigators compare idebenone (90 mg/day, 270 mg/day) and placebo in 180 migraine patients in a double-blind, randomized, placebo-controlled, multicenter trial to study whether Idebenone is superior to placebo in the prevention of episodic migraine with or without aura.
Official title: A Randomized, Double-blinded, Placebo-controlled Trial of Idebenone in the Prevention of Episodic Migraine
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
180
Start Date
2021-12-08
Completion Date
2025-12-31
Last Updated
2025-05-15
Healthy Volunteers
No
Conditions
Interventions
Placebo
Placebo oral tablet, three times a day
90mg Idebenone
Idebenone 30 MG Oral Tablet, three times a day
270mg Idebenone
Idebenone 90 MG Oral Tablet, three times a day
Locations (1)
Kaiming Liu
Hangzhou, Zhejiang, China