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COMPLETED
NCT04154111
NA

Theta Burst Stimulation as a Tool to Decrease Drinking in Treatment-seeking Alcohol Users

Sponsor: Wake Forest University Health Sciences

View on ClinicalTrials.gov

Summary

There is growing interest in the utilization of transcranial magnetic stimulation (TMS) as a novel, non-pharmacologic approach to decreasing alcohol use among treatment-seeking individuals with Alcohol Use Disorder (AUD). The results of this study will be used to determine which of the 2 proposed TMS strategies has a larger effect on drinking behavior (% days abstinent, % heavy drinking days) as well as alcohol cue-reactivity in a 4 month period. These data will pave the way for TMS to be used as an innovative, new treatment option for individuals with AUD.

Key Details

Gender

All

Age Range

21 Years - 75 Years

Study Type

INTERVENTIONAL

Enrollment

147

Start Date

2020-05-26

Completion Date

2026-02-09

Last Updated

2026-06-02

Healthy Volunteers

No

Interventions

DEVICE

Real TBS to the vmPFC

This will be delivered with the Magventure Magpro system; double blinded

DEVICE

Sham TBS to the vmPFC

The MagVenture MagPro system has an integrated active sham that passes current through two surface electrodes placed on the skin beneath the coil.

DEVICE

Real TBS to the dlPFC

This will be delivered with the Magventure Magpro system (double blinded).

DEVICE

Sham TBS to the dlPFC

The MagVenture MagPro system has an integrated active sham that passes current through two surface electrodes placed on the skin beneath the coil.

Locations (1)

Wake Forest School of Medicine

Winston-Salem, North Carolina, United States