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Theta Burst Stimulation as a Tool to Decrease Drinking in Treatment-seeking Alcohol Users
Sponsor: Wake Forest University Health Sciences
Summary
There is growing interest in the utilization of transcranial magnetic stimulation (TMS) as a novel, non-pharmacologic approach to decreasing alcohol use among treatment-seeking individuals with Alcohol Use Disorder (AUD). The results of this study will be used to determine which of the 2 proposed TMS strategies has a larger effect on drinking behavior (% days abstinent, % heavy drinking days) as well as alcohol cue-reactivity in a 4 month period. These data will pave the way for TMS to be used as an innovative, new treatment option for individuals with AUD.
Key Details
Gender
All
Age Range
21 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
147
Start Date
2020-05-26
Completion Date
2026-02-09
Last Updated
2026-06-02
Healthy Volunteers
No
Interventions
Real TBS to the vmPFC
This will be delivered with the Magventure Magpro system; double blinded
Sham TBS to the vmPFC
The MagVenture MagPro system has an integrated active sham that passes current through two surface electrodes placed on the skin beneath the coil.
Real TBS to the dlPFC
This will be delivered with the Magventure Magpro system (double blinded).
Sham TBS to the dlPFC
The MagVenture MagPro system has an integrated active sham that passes current through two surface electrodes placed on the skin beneath the coil.
Locations (1)
Wake Forest School of Medicine
Winston-Salem, North Carolina, United States