Clinical Research Directory
Browse clinical research sites, groups, and studies.
A Study of Patidegib Topical Gel, 2%, for the Reduction of Disease Burden of Persistently Developing Basal Cell Carcinomas in Patients With Non-Gorlin High Frequency BCC
Sponsor: Sol-Gel Technologies, Ltd.
Summary
This is a multicenter, randomized, double-blind, stratified, vehicle-controlled study of the efficacy and safety of Patidegib Topical Gel, 2%, applied topically twice daily to the face of adult participants with non-Gorlin HF-BCC (high-frequency basal cell carcinoma). Participants will be randomized (1:1) to receive either Patidegib Topical Gel, 2%, or Vehicle for 9 months. Randomization will be stratified by gender. The primary endpoint is the number of nSEB (surgically eligible basal cell carcinoma) that develop on the face over the 9 month period. The primary end point will be assessed by imaging and tracking of BCCs consistently throughout the study in order to identify nSEBs.
Official title: A Multicenter, Randomized, Double Blind, Vehicle-controlled, Phase 2 Efficacy and Safety Study of Patidegib Topical Gel, 2%, for the Reduction of Disease Burden of Persistently Developing Basal Cell Carcinomas (BCCs) in Patients With Non-Gorlin High Frequency BCC
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
50
Start Date
2019-12-20
Completion Date
2021-04-23
Last Updated
2026-07-21
Healthy Volunteers
No
Conditions
Interventions
Patidegib Topical Gel, 2%
Patidegib Topical Gel, 2%
Patidegib Topical Gel, Vehicle
Patidegib Topical Gel, Vehicle
Locations (14)
Axiom Research, LLC
Apple Valley, California, United States
Axiom Research, LLC
Colton, California, United States
Center for Dermatology Clinical Research, Inc.
Fremont, California, United States
Dermatology Research Associates
Los Angeles, California, United States
The Dermatology Center of Newport
Newport Beach, California, United States
Palm Beach Dermatology Research
Delray Beach, Florida, United States
Leavitt Medical Associates of Florida
Ormond Beach, Florida, United States
PellePharm Investigative Site
Saint Augustine, Florida, United States
The Indiana Clinical Trials Center
Plainfield, Indiana, United States
Grekin Skin Institute
Warren, Michigan, United States
PellePharm Investigative Site
Henderson, Nevada, United States
Skin Laser and Surgery Specialists of NY&NJ
Hackensack, New Jersey, United States
Duke University Medical Center
Durham, North Carolina, United States
University of Utah
Murray, Utah, United States