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RECRUITING
NCT04166877
PHASE4

Magnesium Infusion for Pain Management in Critically Ill Trauma Patients

Sponsor: University of California, Davis

View on ClinicalTrials.gov

Summary

Magnesium is a naturally occurring mineral that is important for your body and brain. Magnesium sulfate (study drug) is a medication containing magnesium that is commonly used to improve low blood levels of magnesium. Magnesium sulfate has also proven to be successful in managing pain before and after surgery. However, this drug has primarily been used for pain control in patients undergoing surgery. Patients in the ICU with injuries also need good pain control. Using magnesium may assist in decreasing narcotic (pain reliever) requirements and provide another non-narcotic drug for pain control. The purpose of this study is to test the effectiveness of continuous, intravenous (into or within a vein using a needle) administration of magnesium sulfate for pain control in trauma patients admitted to the adult Intensive Care Unit. This will be compared to intravenous normal saline (salt solution).

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

156

Start Date

2019-12-07

Completion Date

2026-12-31

Last Updated

2025-11-26

Healthy Volunteers

No

Interventions

DRUG

Magnesium Sulfate in Parenteral Dosage Form

IV bolus followed by continuous infusion for 24 hours

DRUG

Normal saline placebo

IV bolus followed by continuous infusion for 24 hours

Locations (1)

UC Davis Health

Sacramento, California, United States