Clinical Research Directory
Browse clinical research sites, groups, and studies.
Magnesium Infusion for Pain Management in Critically Ill Trauma Patients
Sponsor: University of California, Davis
Summary
Magnesium is a naturally occurring mineral that is important for your body and brain. Magnesium sulfate (study drug) is a medication containing magnesium that is commonly used to improve low blood levels of magnesium. Magnesium sulfate has also proven to be successful in managing pain before and after surgery. However, this drug has primarily been used for pain control in patients undergoing surgery. Patients in the ICU with injuries also need good pain control. Using magnesium may assist in decreasing narcotic (pain reliever) requirements and provide another non-narcotic drug for pain control. The purpose of this study is to test the effectiveness of continuous, intravenous (into or within a vein using a needle) administration of magnesium sulfate for pain control in trauma patients admitted to the adult Intensive Care Unit. This will be compared to intravenous normal saline (salt solution).
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
156
Start Date
2019-12-07
Completion Date
2026-12-31
Last Updated
2025-11-26
Healthy Volunteers
No
Conditions
Interventions
Magnesium Sulfate in Parenteral Dosage Form
IV bolus followed by continuous infusion for 24 hours
Normal saline placebo
IV bolus followed by continuous infusion for 24 hours
Locations (1)
UC Davis Health
Sacramento, California, United States