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COMPLETED
NCT04179435
NA

Cognitive and Brain Development in Adolescents With Gilles de la Tourette Syndrome

Sponsor: Institut National de la Santé Et de la Recherche Médicale, France

View on ClinicalTrials.gov

Summary

In children with neurodevelopmental disorders, adolescence is usually associated with a reshaping of the clinical picture and symptomatology. Tourette syndrome (TS) is a paradigmal neurodevelopmental syndrome characterised by involuntary paroxysmal movements (motor tics) and vocalisation (vocal tics) often associated with various psychiatric disorders. The neuronal and cognitive mechanisms associated with TS symptoms improvement during adolescence, or the persistence in adulthood remains unknown, and this is what we aim to address in this study.

Official title: Développement Cognitif et cérébral Chez Les Adolescents Souffrants d'un Syndrome de Gilles de la Tourette

Key Details

Gender

All

Age Range

13 Years - 18 Years

Study Type

INTERVENTIONAL

Enrollment

132

Start Date

2019-12-11

Completion Date

2024-06-18

Last Updated

2026-06-05

Healthy Volunteers

Yes

Interventions

BEHAVIORAL

Behavioral testing on cognitive computerized tasks

Testing on cognitive computerized tasks

OTHER

brain MRI

Brain MRI scans

OTHER

TMS

Measure of the cortical inhibitory capacity using TMS measures

Locations (1)

Hôpital de la Pitié-Salpêtrière

Paris, France