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Cognitive and Brain Development in Adolescents With Gilles de la Tourette Syndrome
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France
Summary
In children with neurodevelopmental disorders, adolescence is usually associated with a reshaping of the clinical picture and symptomatology. Tourette syndrome (TS) is a paradigmal neurodevelopmental syndrome characterised by involuntary paroxysmal movements (motor tics) and vocalisation (vocal tics) often associated with various psychiatric disorders. The neuronal and cognitive mechanisms associated with TS symptoms improvement during adolescence, or the persistence in adulthood remains unknown, and this is what we aim to address in this study.
Official title: Développement Cognitif et cérébral Chez Les Adolescents Souffrants d'un Syndrome de Gilles de la Tourette
Key Details
Gender
All
Age Range
13 Years - 18 Years
Study Type
INTERVENTIONAL
Enrollment
132
Start Date
2019-12-11
Completion Date
2024-06-18
Last Updated
2026-06-05
Healthy Volunteers
Yes
Conditions
Interventions
Behavioral testing on cognitive computerized tasks
Testing on cognitive computerized tasks
brain MRI
Brain MRI scans
TMS
Measure of the cortical inhibitory capacity using TMS measures
Locations (1)
Hôpital de la Pitié-Salpêtrière
Paris, France