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RECRUITING
NCT04192253
PHASE2
Treatment of Locally Advanced VULvar CArcinoma in a Neoadjuvant Setting With Carboplatin and Paclitaxel Chemotherapy (VULCANize)
Sponsor: The Netherlands Cancer Institute
View on ClinicalTrials.gov
Summary
Vulvar cancer is a rare malignancy. Surgery is the treatment of choice, but frequently causes invalidating and chronic postoperative morbidity, especially in patients with high stage disease. Theoretically, downstaging with neoadjuvant chemotherapy could shrink the tumour, making surgical treatment less extensive thereby diminishing the chance for morbidity.
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
51
Start Date
2020-01-14
Completion Date
2029-01-01
Last Updated
2022-10-19
Healthy Volunteers
No
Interventions
DRUG
Paclitaxel and Carboplatin
Paclitaxel 175 mg/m2 and Carboplatin AUC 5 in a 3 weekly schedule
Locations (1)
NKI-AVL
Amsterdam, Netherlands