Clinical Research Directory

Inclusion Criteria: * Diabetic: antecedent - treatment - or glycemia\> = 1.26 g / dl - or HbA1C\> = 6.5% and or * Obese: BMI\> = 30 and or * Metabolic syndrome defined AND * Patient having given written consent to participate in the study or collection of the consent of the witness * Social insured patient (excluding AME) * Patient willing to comply with all procedures of the study and its duration AND Patient also presenting a pathology among: * Cardiology: * Coronary patient(history of myocardial infarction, coronary bypass, or coronary angioplasty or stenosis greater than 50% on an epicardial vessel documented on coronary angiography) * Patient with systolic or diastolic heart failure * Patient with atrial fibrillation * Patient with aortic stenosis (Vmax\> 2.5 m / s) * Patient with high blood pressure * neurology: * ischemic stroke * intracerebral hemorrhage * transient ischemic attack * diabetology: * Obesity without diabetes * Diabetes T2 * T1 diabetes * Monogenic Diabetes / MODY * African Diabetes * Diabetes secondary to pancreatopathy / liver cirrhosis * Diabetes post transplantation / post immunotherapy * Diabetes associated with Steinert's disease * hepatology: hepatological pathology * nephrology: nephrology Exclusion Criteria: * Unscheduled hospitalization less than 3 months old * Ongoing treatment : * Cytotoxic chemotherapy * Radiotherapy * HIV and / or HCV and / or active HBV infection * OMS score\> = 2 * Pregnant woman