Clinical Research Directory

Inclusion Criteria: 1. Woman between the ages of 30 and 65 (both inclusive). 2. Able to read and understand the Patient Information Sheet and the Informed Consent form. 3. Acceptance in the participation of the essay and signature of the Informed Consent form. 4. ASC-US or LSIL or AG-US cytological result (maximum 3 months prior to inclusion) with concordant colposcopic image (performed at the screening visit). 5. High risk HPV positive by PCR performed at screening visit. 6. Is able, at the discretion of the researcher, to comply with the requirements of the trial and without hindrance to follow the instructions and assessments throughout it. Exclusion Criteria: 1. Clinically relevant immune system alterations, or any other autoimmune disease or in treatment with immunosuppressants. 2. Non-diagnosed abnormal genital hemorrhage (during the 6 months prior to the screening visit). 3. To had been vaccinated against HPV. 4. Other symptomatic vulvovaginal infections. 5. Surgical cervical excision in the last year or total hysterectomy. 6. Previous history of gynecological cancer. 7. Participation in any other clinical trial at present or in the 4 weeks prior to the inclusion of the trial. 8. Any planned surgery that prevents the correct compliance with the guidelines. 9. Use of vaginal contraceptives or other vaginal hormonal treatments. 10. Contraindications for the use of Papilocare® gel or known allergies to any of its components. 11. Women of childbearing age who do not use effective contraceptive methods, pregnant women, with suspicion of pregnancy or woman who are breastfeeding.