Clinical Research Directory

Inclusion Criteria: * Fluent in English * Cognitively normal or diagnosis of aMCI * Stable medical condition for 3 months prior to screening visit * Stable medications for 4 weeks prior to the screening and study visits * Clinical laboratory values must be within normal limits or, if abnormal, must be judged to be clinically insignificant by the study physician Exclusion Criteria: * A diagnosis of dementia * History of a clinically significant stroke * Current evidence or history in past two years of epilepsy, head injury with loss of consciousness, any major psychiatric disorder including psychosis, major depression, bipolar disorder * Diabetes (type I or type II) insulin dependent and non-insulin dependent diabetes mellitus * Current or past regular use of insulin or any other anti-diabetic medication within 2 months of screening visit. * History of seizure within past five years * Pregnancy or possible pregnancy. * Use of anticoagulants warfarin (Coumadin) and dabigatran (Pradaxa) * Residence in a skilled nursing facility at screening * Use of an investigational agent within two months of screening visit * Regular use of alcohol, narcotics, anticonvulsants, anti-parkinsonian medications, or any other exclusionary medications