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4beta-hydroxycholesterol in Cirrhosis
Sponsor: University of Oulu
Summary
The aim is to evaluate the levels of oxysterols and especially 4beta-hydroxycholesterol in patients with liver cirrhosis. Three cirrhosis cohorts are recruited: patients treated with spironolactone, patients treated with rifaximin, patients without spironolactone or rifaximin. Also three other control cohorts are recruited: patients with pneumonia, patients with Crohn's disease, patients with ulcerative colitis. The effect of the cirrhosis and its medications spironolactone and rifaximin are compared to control groups.
Official title: 4beta-hydroksikolesteroli Maksakirroosissa
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
120
Start Date
2019-12-01
Completion Date
2027-12-31
Last Updated
2026-05-05
Healthy Volunteers
No
Conditions
Interventions
There is no intervention, only research blood samples are collected
Research blood samples collected
Locations (1)
Oulu University Hospital
Oulu, Finland