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Comparing Efficacy of Microwave Vs Embolization Treatment for Adenomyosis
Sponsor: Karolinska Institutet
Summary
Single blinded randomized controlled study of symptom improvement after uterine artery embolization (UAE) versus ultrasound guided percutaneous/transvaginal microwave ablation, evaluated by validated questionnaires. Adenomyosis is a benign condition causing pain and bleeding disorders in many women. Hysterectomy has historically been the golden standard for treatment as well as (postoperatively) diagnosis of the disease. In accordance with refined diagnostic tools such as ultrasound and/or MRI, minimally invasive treatments for adenomyosis are being explored. We plan to compare two minimally invasive techniques: embolization of the uterine artery (a commonly used procedure) and microwave ablation of adenomyotic tissue (previously only in clinical use in China).
Official title: Single Blinded Randomized Controlled Study of Symptom Improvement After Uterine Artery Embolization (UAE) Versus Ultrasound Guided Percutaneous/transvaginal Microwave Ablation, Evaluated by Validated Questionnaires
Key Details
Gender
FEMALE
Age Range
30 Years - 55 Years
Study Type
INTERVENTIONAL
Enrollment
70
Start Date
2020-09-16
Completion Date
2026-06-30
Last Updated
2024-11-20
Healthy Volunteers
No
Conditions
Interventions
Microwave treatment via needle antenna
Microwave treatment via needle antenna, (Emprint Covidien microwave ablation system) either percutaneous or vaginally administrated
Embolization of uterine artery or branches thereof (routine treatment where polyvinyl alcohol particles are released into the predefined bloodstream)
Embolization via percutaneous catheter
Locations (1)
Danderyd Hospital
Stockholm, Sweden