Clinical Research Directory

Inclusion Criteria: * Painful osteoarthritis in the thumb base and radiological arthritis (Eaton Littler class 2-3) and clinical signs of thumb base osteoarthritis (pain at palpation of the thumb base joint and pain during grinding test). * Pain at rest. * Conservative treatment \>6 months (activity modification, splinting, painkillers or thumb base steroid or PRP injection) Exclusion Criteria: * Rheumatoid arthritis. * Ongoing infection in the hand or wrist. - * History of gout or pseudo gout. * Inability to co-operate with the follow-up protocol (language difficulties, severe psychiatric disorder, cognitive impairment, drug addiction). * Intra-articular injection in the affected joint within 6 months. * Eaton Littler class 4 (STT joint involved).