Clinical Research Directory

1. Intervention At the community-level, eligibility includes: Inclusion Criteria: * Location in Dosso, Tahoua, Maradi, Zinder, or Tillabéri regions * Population 250 to 2,499\* * Distance \> 5 km from district headquarters town * Distinguishable from neighboring communities * Verbal consent of community leader(s) Exclusion criteria: * Inaccessible or unsafe for study team * "Quartier" designation on national census \*Population size as estimated from the most recent national census or projections At the individual-level, eligibility includes: Inclusion criteria: * Age 1-59 months * Primary residence in a study community * Verbal consent of caregiver/guardian for study participation * Weight ≥ 3.0 kg (\*no weight limits in communities using age-based dosing) Exclusion criteria: • Known allergy to macrolides 2. Population-based sample collections At the community-level, eligibility includes: Inclusion Criteria: * Location in Dosso * Distinguishable from neighboring communities * Verbal consent of community leader(s) Exclusion criteria: * Inaccessible or unsafe for the study team * Included in MORDOR trials * Not randomly selected * Received treatment prior to sample collection At the individual-level, eligibility includes: Inclusion Criteria: * Age 1-59 months or 7-12 years or caregiver/guardian of a child eligible for treatment * Primary residence in a study community selected for sample collections * Verbal consent of caregiver/guardian for study participation Exclusion criteria: • An individual is not on the list of randomly selected participants from the census