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ACTIVE NOT RECRUITING
NCT04232696
NA

Neuspera's Implantable Sacral Nerve Stimulation System in Patients With Symptoms of Urinary Urgency Incontinence (UUI)

Sponsor: Neuspera Medical, Inc.

View on ClinicalTrials.gov

Summary

Prospective, multi-center, single-arm, seamless phase-pivotal study conducted in participants diagnosed with UUI who have failed or could not tolerate more conservative treatment. The trial will be conducted in two phases. Objective of Phase I: To assess the utilization of the system during the Sacral Nerve Stimulation (SNS) trial period and to help inform the length of hours of daily stimulation to be used in Phase II of the trial. Objective of Phase II: To assess the safety and efficacy of the Neuspera SNS System at 6-months for the primary efficacy endpoint and at 12 months for secondary safety and efficacy endpoints.

Official title: Clinical Study of Neuspera's Implantable Sacral Nerve Stimulation (SNS) System in Patients With Symptoms of Urinary Urgency Incontinence (UUI)

Key Details

Gender

All

Age Range

22 Years - Any

Study Type

INTERVENTIONAL

Enrollment

331

Start Date

2019-12-13

Completion Date

2026-12

Last Updated

2025-11-03

Healthy Volunteers

No

Interventions

DEVICE

Neuspera Implantable Sacral Nerve Stimulation System

Stimulation of the Sacral Nerve.

Locations (34)

Genesis Healthcare Partners

Encinitas, California, United States

Kaiser Permanente, LAMC

Los Angeles, California, United States

Kaiser Permanente

San Diego, California, United States

Clinical Research Center of Florida

Pompano Beach, Florida, United States

Florida Urology Partners, LLC

Tampa, Florida, United States

Midtown Urology

Atlanta, Georgia, United States

Meridian Clinical Research

Savannah, Georgia, United States

Comprehensive Urologic Care

Lake Barrington, Illinois, United States

Women's Health Advantage

Fort Wayne, Indiana, United States

Indiana University School of Medicine

Indianapolis, Indiana, United States

University of Kansas Hospital

Kansas City, Kansas, United States

UofL Health System (University of Louisville)

Louisville, Kentucky, United States

Ochsner Medical

New Orleans, Louisiana, United States

University of Michigan Health - West

Wyoming, Michigan, United States

University of Minnesota

Minneapolis, Minnesota, United States

Minnesota Urology

Woodbury, Minnesota, United States

Specialty Research of St. Louis

St Louis, Missouri, United States

Adult & Pediatric Urology P.C.

Omaha, Nebraska, United States

Weill Cornell Medical College

New York, New York, United States

Premier Medical Group

Poughkeepsie, New York, United States

Associated Medical Professionals of NY

Syracuse, New York, United States

MetroHealth

Cleveland, Ohio, United States

The Oregon Clinic Urogynecology West

Portland, Oregon, United States

The Institute for Female Pelvic Medicine and Reconstructive Surgery

North Wales, Pennsylvania, United States

Southern shores urogynecology

Myrtle Beach, South Carolina, United States

Southern Urogynecology

West Columbia, South Carolina, United States

Center for Pelvic Health

Franklin, Tennessee, United States

Urology Austin

Austin, Texas, United States

Urology Clinics of North Texas (Dallas Center for Pelvic Medicine)

Dallas, Texas, United States

Virginia Mason

Seattle, Washington, United States

University of Washington

Seattle, Washington, United States

Universiteit Antwerpen

Antwerp, Belgium

Maastricht University Medical Center

Maastricht, Netherlands

Erasmus University Medical Center

Rotterdam, Netherlands