Clinical Research Directory

Simplified Inclusion Criteria: * Clinical diagnosis of Stargardt disease (STGD1) * Has at least two ABCA4 disease-causing mutations, unless authorized by sponsor * Has a best-corrected visual acuity (BCVA) greater than approximately 20/160 in at least one eye * Healthy as judged by investigator * Able and willing to comply with study requirements, restrictions and instructions and is likely to complete the 24-month study * Has been invited to participate in this extension, and has signed and dated the informed consent forms (or assent where appropriate) to participate * Female of childbearing potential has signed the attestation on contraception requirements Simplified Exclusion Criteria: * Is lactating or pregnant * Has a medical condition likely to prevent compliance with the protocol and/or interfere with absorption of ALK-001 or performance of study procedures * Has abnormal laboratory result(s) at screening * Has an ocular disorder that may confound ocular assessments * Has a history of ocular intervention within 90 days of screening