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Trifecta-Kidney cfDNA-MMDx Study
Sponsor: University of Alberta
Summary
Demonstrate the relationship between DD-cfDNA levels and HLA antibodies in blood, and the Molecular Microscope® (MMDx) Diagnostic System results in indication biopsies.
Official title: Trifecta-Kidney cfDNA-MMDx Study: Comparing the DD-cfDNA Test to MMDx Microarray Test, Central HLA Antibody Test, and Histology.
Key Details
Gender
All
Age Range
Any - Any
Study Type
OBSERVATIONAL
Enrollment
300
Start Date
2019-12-01
Completion Date
2027-12
Last Updated
2026-03-18
Healthy Volunteers
No
Conditions
Interventions
MMDx
Portion of kidney transplant indication biopsy
Prospera
Transplant patient blood sample
HLA antibody
Transplant patient blood sample
Locations (31)
Tampa General Hospital
Tampa, Florida, United States
University of Maryland School of Medicine
Baltimore, Maryland, United States
The Johns Hopkins University, School of Medicine
Baltimore, Maryland, United States
Detroit Medical Center, Harper University Hospital of Wayne State University
Detroit, Michigan, United States
Henry Ford Hospital
Detroit, Michigan, United States
Barnes-Jewish Hospital, Washington University at St. Louis
St Louis, Missouri, United States
University Hospitals Cleveland Medical Ctr.
Cleveland, Ohio, United States
Cleveland Clinic
Cleveland, Ohio, United States
Intermountain Transplant Services
Murray, Utah, United States
Virginia Commonwealth University Medical Center
Richmond, Virginia, United States
Division of Nephrology & UW Organ Transplant Center University of Washington
Seattle, Washington, United States
Department of Nephrology, The Royal Melbourne Hospital 1 South East
Melbourne, Australia
University of Alberta, Department of Medicine
Edmonton, Alberta, Canada
ST. Paul's Hospital, 6A Providence Building, 1081 Burrard Street
Vancouver, British Columbia, Canada
University Hospital Merkur Renal Division
Zagreb, Croatia
Institute for Clinical and Experimental Medicine (IKEM)
Prague, Czechia
Charite-Medical University of Berlin Department of Nephrology
Berlin, Germany
Centre of Nephrology, Vilnius University Hospital Santaros Klinikos
Vilnius, Lithuania
Department of Nephrology and Transplantation Medical University in Bialystok
Bialystok, Poland
University Hospital nr1 Bydgoszcz, Klinika Transplantologii
Bydgoszcz, Poland
Medical University of Gdańsk Klinika Nefrologii Transplantologii i Chorób Wewnętrznych
Gdansk, Poland
Medical University of Silesia
Katowice, Poland
Department of Transplantation and General Surgery, Wojewodzki Hospital
Poznan, Poland
Department of Nephrology, Transplantation and Internal Medicine, University Hospital n.2
Szczecin, Poland
Pomeranian Medical University, Samodzielny Publiczny Woj. Szpital Zespolony, Oddzial Nefrologii i Transplantacji Nerek
Szczecin, Poland
Medical University of Warsaw, Department of Transplantation Medicine, Nephrology and Internal Diseases
Warsaw, Poland
Transplant Medicine & Nephrology Clinic, Medical University of Warsaw
Warsaw, Poland
The Children's Memorial Health Institute, Department of Nephrology, Kidney Transplantation and Hypertension
Warsaw, Poland
Wroclaw Medical University, Department of Nephrology and Transplantation Medicine
Wroclaw, Poland
Department of Nephrology, University Medical Centre
Ljubljana, Slovenia
University Hospital Zurich
Zurich, Switzerland