Clinical Research Directory

Child Inclusion Criteria: * Be at least 3 years old and no more than 8 years old * ADHD medication naive or have not had an adequate trial of stimulant medications * Have ≥5 inactivity or ≥5 hyperactivity symptoms rated as 1 or 2 on the Vanderbilt * Have a CGI-S-ADHD rating ≥4 and \<7 Child Exclusion Criteria: * Severe ADHD (CGI-S-ADHD score of greater than 6) Parent Inclusion Criteria: * Be at least 21 years old and English-speaking * Meet full DSM-5 criteria for ADHD (any subtype) * Have findings on physical examination, laboratory studies, vital signs, and electrocardiogram judged to be normal for age with no contraindications for stimulant medication * Have pulse and blood pressure (BP) within 95% of age and gender mean * Women of childbearing potential agree to use a medically accepted contraception method consistently * Parents with common comorbid conditions will be included provided that: (a) they do not report active suicidal ideation with intent (i.e. Beck Depression Inventory (BDI)-II score of 2 or 3 to Q9 which assesses suicidal thoughts); and (b) if receiving an antidepressant medication, their medication is well-tolerated, has not changed within 30 days, and the prescribing physician approves of their participation in the study * Must have regular access to a computer or phone that can be used to deliver the behavioral parent training Parent Exclusion Criteria: * History of allergic or other severe negative reactions to study medications * Substance abuse in the past 3 months, or a positive baseline urinary toxic screen that is not explained by a time-limited medical circumstance * Current bipolar disorder, schizophrenia, psychoses, or other primary psychiatric disorder requiring other immediate treatment * History of chronic/acute medical disorder for which stimulant therapy would be contraindicated (e.g., glaucoma, hypertension) * Stimulant medication for ADHD in the past 30 days * Is pregnant