Clinical Research Directory
Browse clinical research sites, groups, and studies.
Induced Membrane Properties in Children and Adults
Sponsor: Centre Hospitalier Universitaire, Amiens
Summary
Bone reconstruction in critical sized defect (CSD) remains a real challenge in orthopedic surgery in children and adults. The Masquelet technique is an innovative therapeutic technique, which offers a bone reconstruction in two steps, by the formation of an induced membrane (IM) around a polymethylmethacrylate (PMMA) spacer placed into the bone defect. After, PMMA removal, the cavity is filled with corticocancellous graft allowing bone healing. Up to date, all angiogenesis and osteogenic properties of IM remain unknown. The purpose of this study is to characterize angiogenesis and osteogenic properties of IM in children and adults.
Key Details
Gender
All
Age Range
9 Months - 60 Years
Study Type
INTERVENTIONAL
Enrollment
50
Start Date
2019-05-23
Completion Date
2030-01
Last Updated
2025-06-08
Healthy Volunteers
No
Interventions
harvesting induced membrane
The induced membrane will be harvested during the second step of the bone reconstruction.
Locations (1)
CHU Amiens
Amiens, France